25-HYDROXYCHOLESTEROL AND 27-HYDROXYCHOLESTEROL INHIBIT HUMAN ROTAVIRUS INFECTION BY SEQUESTERING VIRAL PARTICLES INTO LATE ENDOSOMES

25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes

A novel innate immune strategy, involving specific cholesterol oxidation products as effectors, has begun to reveal connections between cholesterol metabolism and immune response against viral infections.Indeed, 25-hydroxycholesterol (25HC) and 27-hydroxycholesterol (27HC), physiologically produced by enzymatic oxidation of cholesterol, act as inhi

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Approximation of the Cox survival regression model by MCMC Bayesian Hierarchical Poisson modelling of factors associated with childhood mortality in Nigeria

Abstract The need for more pragmatic approaches to achieve sustainable development goal on childhood mortality reduction necessitated this study.Simultaneous study of the influence of where the children live and the censoring nature of children survival data is scarce.We identified the compositional and contextual factors associated with under-five

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A Systematic Review on Traditional Medicinal Plants Used for the Treatment of Viral and Fungal Infections in Ethiopia

Yibeltal Aschale,1 Muluken Wubetu,2 Abtie Abebaw,1 Tadesse Yirga,3 Awoke Minwuyelet,4 Milkiyas Toru1 1Department of Medical Laboratory Sciences, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia; 3Department of Pediatrics

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